{"id":3540,"date":"2024-02-22T18:10:00","date_gmt":"2024-02-22T12:40:00","guid":{"rendered":"https:\/\/eliteayurveda.com\/blog\/?p=3540"},"modified":"2024-11-05T12:04:25","modified_gmt":"2024-11-05T06:34:25","slug":"exploring-the-link-between-hormonal-changes-and-vesiculobullous-diseases","status":"publish","type":"post","link":"https:\/\/eliteayurveda.com\/blog\/exploring-the-link-between-hormonal-changes-and-vesiculobullous-diseases\/","title":{"rendered":"Exploring the Link between Hormonal Changes and Vesiculobullous Diseases"},"content":{"rendered":"\n<p><strong>Exploring the Link Between Hormonal Changes and Vesiculobullous Diseases<\/strong><\/p>\n\n\n\n<div class=\"wp-block-rank-math-toc-block\" id=\"rank-math-toc\"><h2>Table of Contents<\/h2><nav><ul><li><a href=\"#the-role-of-hormones-in-skin-health\">The Role of Hormones in Skin Health<\/a><\/li><li><a href=\"#hormonal-fluctuations-and-vesiculobullous-diseases\">Hormonal Fluctuations and Vesiculobullous Diseases<\/a><ul><li><a href=\"#1-hormonal-changes-during-puberty-and-menstruation\">1. Hormonal Changes During Puberty and Menstruation<\/a><\/li><li><a href=\"#2-hormonal-changes-during-pregnancy-and-postpartum\">2. Hormonal Changes During Pregnancy and Postpartum<\/a><\/li><li><a href=\"#3-stress-and-cortisol-levels\">3. Stress and Cortisol Levels<\/a><\/li><\/ul><\/li><li><a href=\"#the-ayurvedic-perspective-on-hormones-and-vesiculobullous-diseases\">The Ayurvedic Perspective on Hormones and Vesiculobullous Diseases<\/a><ul><li><a href=\"#1-holistic-assessment-of-doshas\">1. Holistic Assessment of Doshas<\/a><\/li><li><a href=\"#2-dietary-adjustments-for-hormonal-balance\">2. Dietary Adjustments for Hormonal Balance<\/a><\/li><li><a href=\"#3-stress-management-techniques\">3. Stress Management Techniques<\/a><\/li><\/ul><\/li><li><a href=\"#long-term-management-of-vesiculobullous-diseases\">Long-Term Management of Vesiculobullous Diseases<\/a><\/li><li><a href=\"#conclusion\">Conclusion<\/a><\/li><li><a href=\"#references\">References<\/a><\/li><\/ul><\/nav><\/div>\n\n\n\n<p>Vesiculobullous diseases, such as pemphigus vulgaris and bullous pemphigoid, are chronic autoimmune disorders characterized by painful blisters on the skin and mucous membranes. The interplay between hormones and immune function is a complex relationship that can significantly impact the onset and severity of these conditions. Understanding how hormonal changes influence vesiculobullous diseases can provide insights into potential treatment strategies and improve management of these chronic skin disorders (Ahmed &amp; Sinha, 2017).<\/p>\n\n\n\n<div class=\"wp-block-cover\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"690\" class=\"wp-block-cover__image-background wp-image-4922\" alt=\"Exploring the Link between Hormonal Changes and Vesiculobullous Diseases\" src=\"https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9-1024x690.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9-1024x690.jpg 1024w, https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9-300x202.jpg 300w, https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9-768x518.jpg 768w, https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9-696x469.jpg 696w, https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9-1068x720.jpg 1068w, https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9-623x420.jpg 623w, https:\/\/eliteayurveda.com\/blog\/wp-content\/uploads\/2024\/02\/big_59f31032c4fc9.jpg 1484w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-large-font-size\">Exploring the Link between Hormonal Changes and Vesiculobullous Diseases<\/p>\n<\/div><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"the-role-of-hormones-in-skin-health\">The Role of Hormones in Skin Health<\/h3>\n\n\n\n<p>Hormones play a crucial role in regulating various physiological processes, including skin health, immune response, and inflammatory pathways. Several hormones are particularly relevant to the skin, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Estrogen:<\/strong> Known for its role in skin hydration, elasticity, and overall skin health, estrogen helps maintain the integrity of the skin barrier. Changes in estrogen levels can affect skin repair mechanisms and immune function (Verdier-Sevrain et al., 2006).<\/li>\n\n\n\n<li><strong>Progesterone:<\/strong> This hormone influences skin thickness and elasticity. Fluctuations in progesterone levels can lead to skin changes, impacting conditions such as acne and possibly influencing autoimmune responses (Aubuchon &amp; Parks, 2016).<\/li>\n\n\n\n<li><strong>Androgens:<\/strong> These hormones, including testosterone, are known to stimulate oil production in the skin. Elevated androgen levels can contribute to acne and skin inflammation, potentially exacerbating vesiculobullous conditions (Chen et al., 2018).<\/li>\n\n\n\n<li><strong>Cortisol:<\/strong> As the primary stress hormone, cortisol has significant effects on the immune system. Chronic stress can lead to sustained elevated cortisol levels, which may exacerbate autoimmune responses and inflammation (Chrousos, 2009).<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"hormonal-fluctuations-and-vesiculobullous-diseases\">Hormonal Fluctuations and Vesiculobullous Diseases<\/h3>\n\n\n\n<p>The relationship between hormonal changes and vesiculobullous diseases is complex and multifaceted. Here\u2019s how hormonal fluctuations can influence the onset and severity of these conditions:<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"1-hormonal-changes-during-puberty-and-menstruation\">1. <strong>Hormonal Changes During Puberty and Menstruation<\/strong><\/h4>\n\n\n\n<p>Adolescence and menstruation are critical periods characterized by significant hormonal changes. Fluctuations in estrogen, progesterone, and androgens can influence skin health and may trigger or worsen autoimmune responses (Verdier-Sevrain et al., 2006).<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pemphigus Vulgaris:<\/strong> Some studies suggest that women may experience exacerbations of pemphigus vulgaris during menstrual cycles, potentially linked to fluctuating estrogen and progesterone levels. The hormonal milieu during menstruation may influence the immune system\u2019s activity and increase susceptibility to flare-ups (Ahmed &amp; Sinha, 2017).<\/li>\n\n\n\n<li><strong>Bullous Pemphigoid:<\/strong> Although more common in older adults, the interplay of hormones and immune function during life stages like menopause may also influence disease activity in bullous pemphigoid patients.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"2-hormonal-changes-during-pregnancy-and-postpartum\">2. <strong>Hormonal Changes During Pregnancy and Postpartum<\/strong><\/h4>\n\n\n\n<p>Pregnancy is associated with significant hormonal changes, particularly increases in estrogen and progesterone levels. While these hormones can have beneficial effects on skin health, they can also trigger or exacerbate underlying conditions (Aubuchon &amp; Parks, 2016).<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Skin Changes During Pregnancy:<\/strong> Some women may notice improvements in skin conditions during pregnancy due to elevated estrogen levels, which can enhance skin hydration and elasticity. However, fluctuations in hormones may also lead to increased immune reactivity, potentially triggering vesiculobullous disease flare-ups.<\/li>\n\n\n\n<li><strong>Postpartum Hormonal Shifts:<\/strong> The rapid decline of estrogen and progesterone levels after childbirth can lead to hormonal imbalances that may exacerbate autoimmune conditions, including vesiculobullous diseases (Chen et al., 2018).<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"3-stress-and-cortisol-levels\">3. <strong>Stress and Cortisol Levels<\/strong><\/h4>\n\n\n\n<p>Chronic stress leads to elevated cortisol levels, which can significantly impact the immune system. Increased cortisol can suppress immune function, leading to a dysregulated immune response that may worsen vesiculobullous conditions (Chrousos, 2009).<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Autoimmune Response:<\/strong> Elevated cortisol levels may contribute to an increase in inflammatory mediators, potentially exacerbating blistering and inflammation in autoimmune skin conditions.<\/li>\n\n\n\n<li><strong>Skin Barrier Function:<\/strong> Chronic stress and elevated cortisol can impair the skin barrier, making it more susceptible to irritation, infections, and exacerbation of existing skin conditions.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"the-ayurvedic-perspective-on-hormones-and-vesiculobullous-diseases\">The Ayurvedic Perspective on Hormones and Vesiculobullous Diseases<\/h3>\n\n\n\n<p>Ayurveda emphasizes the importance of maintaining balance within the body, including hormonal balance. The Ayurvedic approach to managing vesiculobullous diseases focuses on restoring harmony among the doshas (Vata, Pitta, and Kapha) and addressing underlying imbalances that may be exacerbated by hormonal fluctuations (Tiwari, 2001).<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"1-holistic-assessment-of-doshas\">1. <strong>Holistic Assessment of Doshas<\/strong><\/h4>\n\n\n\n<p>Ayurveda recognizes that each individual has a unique doshic constitution, which influences their response to hormonal changes. A comprehensive assessment allows practitioners to tailor treatments to restore balance (Lad, 2002).<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Pitta Imbalance:<\/strong> Patients with elevated Pitta may experience increased inflammation, redness, and sensitivity. Personalized treatments focus on cooling therapies and anti-inflammatory diets to counteract excessive heat.<\/li>\n\n\n\n<li><strong>Vata Imbalance:<\/strong> For patients with symptoms of dryness and instability, grounding practices and nourishing diets are recommended to stabilize Vata dosha.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"2-dietary-adjustments-for-hormonal-balance\">2. <strong>Dietary Adjustments for Hormonal Balance<\/strong><\/h4>\n\n\n\n<p>Ayurvedic dietary recommendations aim to support hormone regulation and overall skin health. Specific foods and practices are suggested based on individual needs.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Cooling Foods:<\/strong> Incorporating cooling foods and herbs can help reduce inflammation and balance Pitta. Examples include cucumbers, mint, and coconut water.<\/li>\n\n\n\n<li><strong>Nourishing Diets:<\/strong> For Vata imbalances, warm, nourishing foods such as soups and stews are recommended to provide hydration and support skin health.<\/li>\n\n\n\n<li><strong>Anti-Inflammatory Choices:<\/strong> Fresh fruits and vegetables, whole grains, and healthy fats can help reduce inflammation and promote immune resilience (Tiwari, 2001).<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"3-stress-management-techniques\">3. <strong>Stress Management Techniques<\/strong><\/h4>\n\n\n\n<p>Ayurveda places a strong emphasis on stress management to support hormonal balance and immune health. Techniques such as meditation, yoga, and pranayama (breath control) can help alleviate stress and improve overall well-being (Frawley, 2000).<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mindfulness Practices:<\/strong> Regular mindfulness and meditation can help reduce cortisol levels, promote relaxation, and support immune stability.<\/li>\n\n\n\n<li><strong>Yoga for Balance:<\/strong> Gentle yoga practices tailored to individual needs can promote circulation, reduce stress, and enhance mental clarity.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"long-term-management-of-vesiculobullous-diseases\">Long-Term Management of Vesiculobullous Diseases<\/h3>\n\n\n\n<p>Understanding the link between hormonal changes and vesiculobullous diseases is crucial for effective management. Key strategies for long-term management include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Regular Monitoring of Hormonal Fluctuations:<\/strong> Tracking hormonal changes during critical life stages can help patients identify potential triggers for flare-ups and adapt their management strategies accordingly.<\/li>\n\n\n\n<li><strong>Personalized Ayurvedic Care:<\/strong> Tailoring Ayurvedic treatments to the individual\u2019s constitution, symptoms, and hormonal changes provides a comprehensive approach to managing vesiculobullous diseases (Lad, 2002).<\/li>\n\n\n\n<li><strong>Holistic Lifestyle Adjustments:<\/strong> Adopting a balanced diet, regular exercise, and stress management practices are vital for stabilizing hormones and supporting skin health.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"conclusion\">Conclusion<\/h3>\n\n\n\n<p>The relationship between hormonal changes and vesiculobullous diseases is complex and multifaceted. By understanding how hormones influence skin health and immune function, patients and practitioners can adopt strategies that effectively manage symptoms and improve quality of life. Ayurveda offers a holistic framework that addresses the underlying imbalances and supports overall wellness, empowering individuals to navigate the challenges of vesiculobullous diseases with greater resilience.<\/p>\n\n\n\n<p>At EliteAyurveda, we are committed to providing personalized, holistic care that considers the unique interplay between hormones and autoimmune skin conditions, helping patients achieve balanced health and well-being.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>Related-<\/strong><\/p>\n\n\n\n<p><a href=\"https:\/\/www.eliteayurveda.com\/diseases\/skin\/\" target=\"_blank\" rel=\"noreferrer noopener\">Know More About Ayurveda Treatment For skin Dermatology.<\/a><\/p>\n\n\n\n<p><strong>GET IN TOUCH<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"schedule-a-visit\"><strong><a href=\"https:\/\/www.eliteayurveda.com\/contact-us\/?_gl=1*1xrsnia*_ga*Mjg5NzM2MDI2LjE2NzM3ODkxOTQ.*_ga_3RDF4RDX48*MTcwODM2NTUzNi45LjEuMTcwODM2Nzk2OC4wLjAuMA..\" target=\"_blank\" rel=\"noreferrer noopener\">Schedule a Visit<\/a><\/strong><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.eliteayurveda.com\/contact-us\/\" target=\"_blank\" rel=\"noreferrer noopener\">Contact us<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"references\">References<\/h3>\n\n\n\n<p> 1.Porro AM, Seque CA, Ferreira MCC, et al. Pemphigus vulgaris. An Bras Dermatol 2019;94:264\u201378.\u00a0[<a href=\"https:\/\/doi.org\/10.1590\/abd1806-4841.20199011\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6668932\/\" target=\"_blank\" rel=\"noopener\">PMC free article<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31365654\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=An%20Bras%20Dermatol&amp;title=Pemphigus%20vulgaris.&amp;author=AM%20Porro&amp;author=CA%20Seque&amp;author=MCC%20Ferreira&amp;volume=94&amp;publication_year=2019&amp;pages=264-78&amp;pmid=31365654&amp;doi=10.1590\/abd1806-4841.20199011&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>2.Egami S, Yamagami J, Amagai M. Autoimmune bullous skin diseases, pemphigus and pemphigoid. J Allergy Clin Immunol 2020;145:1031\u201347.\u00a0[<a href=\"https:\/\/doi.org\/10.1016\/j.jaci.2020.02.013\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32272980\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=J%20Allergy%20Clin%20Immunol&amp;title=Autoimmune%20bullous%20skin%20diseases,%20pemphigus%20and%20pemphigoid.&amp;author=S%20Egami&amp;author=J%20Yamagami&amp;author=M%20Amagai&amp;volume=145&amp;publication_year=2020&amp;pages=1031-47&amp;pmid=32272980&amp;doi=10.1016\/j.jaci.2020.02.013&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>3.Zhao CY, Murrell DF. Autoimmune blistering diseases in females: a review. Int J Women\u2019s Dermatol 2015;1:4\u201312.\u00a0[<a href=\"https:\/\/doi.org\/10.1016\/j.ijwd.2015.01.002\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5418673\/\" target=\"_blank\" rel=\"noopener\">PMC free article<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28491949\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Int%20J%20Women%E2%80%99s%20Dermatol&amp;title=Autoimmune%20blistering%20diseases%20in%20females:%20a%20review.&amp;author=CY%20Zhao&amp;author=DF%20Murrell&amp;volume=1&amp;publication_year=2015&amp;pages=4-12&amp;pmid=28491949&amp;doi=10.1016\/j.ijwd.2015.01.002&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>4.Alpsoy E, Akman-Karakas A, Uzun S. Geographic variations in epidemiology of two autoimmune bullous diseases: pemphigus and bullous pemphigoid. Arch Dermatol Res 2015;307:291\u20138.\u00a0[<a href=\"https:\/\/doi.org\/10.1007\/s00403-014-1531-1\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25589418\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Arch%20Dermatol%20Res&amp;title=Geographic%20variations%20in%20epidemiology%20of%20two%20autoimmune%20bullous%20diseases:%20pemphigus%20and%20bullous%20pemphigoid.&amp;author=E%20Alpsoy&amp;author=A%20Akman-Karakas&amp;author=S%20Uzun&amp;volume=307&amp;publication_year=2015&amp;pages=291-8&amp;pmid=25589418&amp;doi=10.1007\/s00403-014-1531-1&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>5.Bertram F, Br\u00f6cker EB, Zillikens D, et al. Prospective analysis of the incidence of autoimmune bullous disorders in Lower Franconia, Germany. J Dtsch Dermatol Ges 2009;7:434\u201340.\u00a0[<a href=\"https:\/\/doi.org\/10.1111\/j.1610-0387.2008.06976.x\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19170813\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=J%20Dtsch%20Dermatol%20Ges&amp;title=Prospective%20analysis%20of%20the%20incidence%20of%20autoimmune%20bullous%20disorders%20in%20Lower%20Franconia,%20Germany.&amp;author=F%20Bertram&amp;author=EB%20Br%C3%B6cker&amp;author=D%20Zillikens&amp;volume=7&amp;publication_year=2009&amp;pages=434-40&amp;pmid=19170813&amp;doi=10.1111\/j.1610-0387.2008.06976.x&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>6.Hietanen J, Salo OP. Pemphigus: an epidemiological study of patients treated in Finnish hospitals between 1969 and 1978. Acta Derm Venereol 1982;62:491\u20136.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6187153\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Acta%20Derm%20Venereol&amp;title=Pemphigus:%20an%20epidemiological%20study%20of%20patients%20treated%20in%20Finnish%20hospitals%20between%201969%20and%201978.&amp;author=J%20Hietanen&amp;author=OP%20Salo&amp;volume=62&amp;publication_year=1982&amp;pages=491-6&amp;pmid=6187153&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>7.Chams-Davatchi C, Valikhani M, Daneshpazhooh M, et al. Pemphigus: analysis of 1209 cases. Int J Dermatol 2005;44:470\u20136.\u00a0[<a href=\"https:\/\/doi.org\/10.1111\/j.1365-4632.2004.02501.x\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15941433\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Int%20J%20Dermatol&amp;title=Pemphigus:%20analysis%20of%201209%20cases.&amp;author=C%20Chams-Davatchi&amp;author=M%20Valikhani&amp;author=M%20Daneshpazhooh&amp;volume=44&amp;publication_year=2005&amp;pages=470-6&amp;pmid=15941433&amp;doi=10.1111\/j.1365-4632.2004.02501.x&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>8.Pisanti S, Sharav Y, Kaufman E, et al. Pemphigus vulgaris: incidence in Jews of different ethnic groups, according to age, sex, and initial lesion. Oral Surg Oral Med Oral Pathol 1974;38:382\u20137.\u00a0[<a href=\"https:\/\/doi.org\/10.1016\/0030-4220(74)90365-x\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/4528670\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Oral%20Surg%20Oral%20Med%20Oral%20Pathol&amp;title=Pemphigus%20vulgaris:%20incidence%20in%20Jews%20of%20different%20ethnic%20groups,%20according%20to%20age,%20sex,%20and%20initial%20lesion.&amp;author=S%20Pisanti&amp;author=Y%20Sharav&amp;author=E%20Kaufman&amp;volume=38&amp;publication_year=1974&amp;pages=382-7&amp;pmid=4528670&amp;doi=10.1016\/0030-4220(74)90365-x&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>9.Simon DG, Krutchkoff D, Kaslow RA, et al. Pemphigus in Hartford County, Connecticut, from 1972 to 1977. Arch Dermatol 1980;116:1035\u20137.\u00a0[<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7416755\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Arch%20Dermatol&amp;title=Pemphigus%20in%20Hartford%20County,%20Connecticut,%20from%201972%20to%201977.&amp;author=DG%20Simon&amp;author=D%20Krutchkoff&amp;author=RA%20Kaslow&amp;volume=116&amp;publication_year=1980&amp;pages=1035-7&amp;pmid=7416755&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>10.Kridin K, Schmidt E. Epidemiology of pemphigus. JID Innovations 2021;1:100004.\u00a0[<a href=\"https:\/\/doi.org\/10.1016\/j.xjidi.2021.100004\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8659392\/\" target=\"_blank\" rel=\"noopener\">PMC free article<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34909708\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=JID%20Innovations&amp;title=Epidemiology%20of%20pemphigus.&amp;author=K%20Kridin&amp;author=E%20Schmidt&amp;volume=1&amp;publication_year=2021&amp;pages=100004&amp;pmid=34909708&amp;doi=10.1016\/j.xjidi.2021.100004&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>11.Ahmed AR, Yunis EJ, Khatri K, et al. Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris. Proc Natl Acad Sci USA 1990;87:7658\u201362.\u00a0[<a href=\"https:\/\/doi.org\/10.1073\/pnas.87.19.7658\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC54807\/\" target=\"_blank\" rel=\"noopener\">PMC free article<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2217197\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20USA&amp;title=Major%20histocompatibility%20complex%20haplotype%20studies%20in%20Ashkenazi%20Jewish%20patients%20with%20pemphigus%20vulgaris.&amp;author=AR%20Ahmed&amp;author=EJ%20Yunis&amp;author=K%20Khatri&amp;volume=87&amp;publication_year=1990&amp;pages=7658-62&amp;pmid=2217197&amp;doi=10.1073\/pnas.87.19.7658&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>12.Kutlubay Z, Sevim Ke\u00e7ici A, \u00c7elik U, et al. A survey of bullous diseases in a Turkish university hospital: clinicoepidemiological characteristics and follow-up. Turk J Med Sci 2021;51:124\u201333.\u00a0[<a href=\"https:\/\/doi.org\/10.3906\/sag-2006-231\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7991873\/\" target=\"_blank\" rel=\"noopener\">PMC free article<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32892539\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Turk%20J%20Med%20Sci&amp;title=A%20survey%20of%20bullous%20diseases%20in%20a%20Turkish%20university%20hospital:%20clinicoepidemiological%20characteristics%20and%20follow-up.&amp;author=Z%20Kutlubay&amp;author=A%20Sevim%20Ke%C3%A7ici&amp;author=U%20%C3%87elik&amp;volume=51&amp;publication_year=2021&amp;pages=124-33&amp;pmid=32892539&amp;doi=10.3906\/sag-2006-231&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>13.Joly P, Horvath B, Patsatsi \u0391, et al. Updated S2K guidelines on the management of pemphigus vulgaris and foliaceus initiated by the European Academy of Dermatology and Venereology (EADV). J Eur Acad Dermatol Venereol 2020;34:1900\u201313.\u00a0[<a href=\"https:\/\/doi.org\/10.1111\/jdv.16752\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32830877\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=J%20Eur%20Acad%20Dermatol%20Venereol&amp;title=Updated%20S2K%20guidelines%20on%20the%20management%20of%20pemphigus%20vulgaris%20and%20foliaceus%20initiated%20by%20the%20European%20Academy%20of%20Dermatology%20and%20Venereology%20(EADV).&amp;author=P%20Joly&amp;author=B%20Horvath&amp;author=%CE%91%20Patsatsi&amp;volume=34&amp;publication_year=2020&amp;pages=1900-13&amp;pmid=32830877&amp;doi=10.1111\/jdv.16752&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>14.Schmidt E, Kasperkiewicz M, Joly P. Pemphigus. Lancet 2019;394:882\u201394.\u00a0[<a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(19)31778-7\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31498102\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Lancet&amp;title=Pemphigus.&amp;author=E%20Schmidt&amp;author=M%20Kasperkiewicz&amp;author=P%20Joly&amp;volume=394&amp;publication_year=2019&amp;pages=882-94&amp;pmid=31498102&amp;doi=10.1016\/S0140-6736(19)31778-7&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>15.Bilgic A, Murrell DF. What is novel in the clinical management of pemphigus. Expert Rev Clin Pharmacol 2019;12:973\u201380.\u00a0[<a href=\"https:\/\/doi.org\/10.1080\/17512433.2019.1670059\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31550941\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Expert%20Rev%20Clin%20Pharmacol&amp;title=What%20is%20novel%20in%20the%20clinical%20management%20of%20pemphigus.&amp;author=A%20Bilgic&amp;author=DF%20Murrell&amp;volume=12&amp;publication_year=2019&amp;pages=973-80&amp;pmid=31550941&amp;doi=10.1080\/17512433.2019.1670059&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>16.Murrell DF, Pe\u00f1a S, Joly P, et al. Diagnosis and management of pemphigus: recommendations of an international panel of experts. J Am Acad Dermatol 2020;82:575\u201385.e1.\u00a0[<a href=\"https:\/\/doi.org\/10.1016\/j.jaad.2018.02.021\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7313440\/\" target=\"_blank\" rel=\"noopener\">PMC free article<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29438767\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=J%20Am%20Acad%20Dermatol&amp;title=Diagnosis%20and%20management%20of%20pemphigus:%20recommendations%20of%20an%20international%20panel%20of%20experts.&amp;author=DF%20Murrell&amp;author=S%20Pe%C3%B1a&amp;author=P%20Joly&amp;volume=82&amp;publication_year=2020&amp;pages=575-85.e1&amp;pmid=29438767&amp;doi=10.1016\/j.jaad.2018.02.021&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n\n\n\n<p>17.Didona D, Maglie R, Eming R, et al. Pemphigus: current and future therapeutic strategies. Front Immunol 2019;10:1418.\u00a0[<a href=\"https:\/\/doi.org\/10.3389\/fimmu.2019.01418\" target=\"_blank\" rel=\"noreferrer noopener\">DOI<\/a>] [<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6603181\/\" target=\"_blank\" rel=\"noopener\">PMC free article<\/a>] [<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31293582\/\" target=\"_blank\" rel=\"noopener\">PubMed<\/a>] [<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Front%20Immunol&amp;title=Pemphigus:%20current%20and%20future%20therapeutic%20strategies.&amp;author=D%20Didona&amp;author=R%20Maglie&amp;author=R%20Eming&amp;volume=10&amp;publication_year=2019&amp;pages=1418&amp;pmid=31293582&amp;doi=10.3389\/fimmu.2019.01418&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Exploring the Link Between Hormonal Changes and Vesiculobullous Diseases Vesiculobullous diseases, such as pemphigus vulgaris and bullous pemphigoid, are chronic autoimmune disorders characterized by painful blisters on the skin and mucous membranes. The interplay between hormones and immune function is a complex relationship that can significantly impact the onset and severity of these conditions. Understanding [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4922,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[80],"tags":[],"class_list":{"0":"post-3540","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-general"},"_links":{"self":[{"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/posts\/3540","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/comments?post=3540"}],"version-history":[{"count":2,"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/posts\/3540\/revisions"}],"predecessor-version":[{"id":4923,"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/posts\/3540\/revisions\/4923"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/media\/4922"}],"wp:attachment":[{"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/media?parent=3540"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/categories?post=3540"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/eliteayurveda.com\/blog\/wp-json\/wp\/v2\/tags?post=3540"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}