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Millions of people in India suffer from at least one skin condition. You’ve probably heard of the more common ones, such as acne, eczema, and rosacea. In fact, there’s a strong possibility you have one yourself.

There are also a number of uncommon skin problems that you may be unaware of. They can range in severity from minor to fatal. They can have an impact on the quality of life of persons who develop them in some situations.

Continue reading for an overview of some of these lesser-known conditions.

Hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic inflammatory disorder that causes lesions to grow on skin-to-skin contact points on the body. The following are the most prevalent locations for breakouts:

underarms, groin, buttocks, upper thighs, and breasts

Although the etiology of HS is uncertain, hormones are likely to play a role in its development because it often begins around puberty.

The illness affects up to 2% of the population. It is especially common in those who are obese or who smoke. Women are more than three times as likely than men to have HS.

Genetics and the immune system are thought to play a role in who gets the condition.


People who have hidradenitis suppurativa are more likely to have specific conditions (or comorbidities), such as:

inflammatory bowel disease (IBD) acne

Acne conglobata, dissecting cellulitis of the scalp, and pilonidal sinus disease are all part of the follicular occlusion tetrad (a collection of inflammatory skin disorders).

metabolic disorder

PCOS (polycystic ovarian syndrome)

Type 2 diabetes with squamous cell carcinoma of the afflicted skin

The first signs of HS are outbreaks that resemble pimples or boils. These outbreaks could remain on the skin or fade and recur.

If neglected, more severe symptoms like scarring, infection, and breakouts that rupture and produce a foul-smelling fluid might develop.

There is presently no cure for HS, however there are several therapy options to assist control symptoms. These are some examples:

topical ointments, anti-inflammatory medications, injectable biologics, and hormone therapy

In more severe situations, surgery may be recommended.

Psoriasis inversa

Intertriginous psoriasis is another name for inverse psoriasis. This illness, like HS, causes red sores on regions of the body where skin touches skin. These lesions do not resemble boils. They appear smooth and gleaming.

Many persons who have inverse psoriasis have at least one other type of psoriasis on their body. Experts aren’t clear what causes psoriasis, but genetics and the immune system both play a role.

Psoriasis affects roughly 3% of the world’s population, and 3–7% of those with psoriasis have inverse psoriasis.

Because the skin in high-friction parts of the body is sensitive, treating the condition can be challenging. Steroid creams and topical ointments can be beneficial, but they can also cause unpleasant irritation if used excessively.

People with more severe inverse psoriasis may also require UVB light therapy or injectable biologics to manage their illness.

Harlequin ichthyosis

Harlequin ichthyosis is an uncommon genetic condition that causes children to be born with rough, thick skin covered in diamond-shaped scales.

These plates, which are separated by deep fissures, can shape their eyelids, mouth, nose, and ears. They can also impede limb and chest movement.

Around 200 instances have been recorded around the world. The disorder is caused by a mutation in the ABCA12 gene, which permits the body to produce a protein required for normal skin cell formation.

The mutation hinders lipid transfer to the skin’s top layer, resulting in the scale-like plates. Because of the plates, it is more difficult to:

control water loss

combat illness by regulating body temperature

Harlequin ichthyosis is an autosomal recessive condition caused by faulty genes inherited from both parents.

Because biological carriers rarely show symptoms, genetic testing can detect changes in genes and calculate your risk of developing or passing on genetic illnesses.

A stringent regimen of skin-softening emollients and skin-repairing moisturizers is the most popular treatment for harlequin ichthyosis. Oral retinoids may also be utilized in extreme situations.

Morgellons syndrome

Morgellons disease is an uncommon ailment that causes microscopic fibers and particles to emerge from skin wounds, giving the impression that something is crawling on the skin.

The Morgellons Disease is poorly understood, although it affects nearly 14,000 families, according to the Morgellons Research Foundation.

Morgellons disease is most common in middle-aged Caucasian women. It’s also closely linked to Lyme disease.

Because the symptoms are similar to those of a mental health illness known as delusional infestation, some experts assume it is a psychological issue.

The symptoms are unpleasant but not life-threatening. Typical symptoms include:

weariness anxiety sadness itchy skin rashes or sores black fibrous substance in and on the skin

Lesions only affect one part of the body: the head, trunk, or extremities.

There is no standard treatment option for Morgellons disease because it is still poorly understood.

People suffering with the disease are usually encouraged to maintain close contact with their healthcare team and seek therapy for symptoms such as anxiety and depression.


Elastoderma is an uncommon disorder characterized by increased skin looseness in particular parts of the body. As a result, the skin sags or hangs down in loose folds.

It can affect any region of the body, but the neck and extremities, particularly the elbows and knees, are the most usually afflicted.

The illness affects less than one in one million persons worldwide. Elastoderma’s actual cause is unknown. It is assumed to be caused by an excess of elastin, a protein that provides structural support to organs and tissues.

Elastoderma has no cure or recommended treatment. Some people will have surgery to remove the problematic area, although the loose skin often returns after the procedure.

Pilonidal sinusitis

Pilonidal sinus illness causes small holes or tunnels at the buttocks’ base or crease. Because symptoms aren’t always clear, most people don’t seek therapy or even recognize the issue until it causes problems.

It is caused when the hair between the buttocks rubs together. The friction and pressure that results pushes the hair inside, causing it to become ingrown.

This minor illness affects 10 to 26 people in every 100,000. The majority of people with this illness are between the ages of 15 and 30, and men are twice as likely as women to have it.

It frequently affects persons who work occupations that demand long periods of sitting. It is often associated with hidradenitis suppurativa (HS).

A few things influence treatment for an infected pilonidal sinus:

signs and symptoms

the size of the abscess, if it is a new or recurring infection

In most cases, treatment entails removing any visible pus from the affected pilonidal sinus. Antibiotics, hot compresses, and topical ointments are also frequently utilized.

If you’re one of the 40% of people with the illness who has reoccurring abscesses, talk to your doctor about other surgical alternatives.

Pemphigus vegetans

Pemphigus is classified as an autoimmune illness by the National Institutes of Health (NIH)Trusted Source. It causes your immune system to target healthy epidermal cells. The epidermis is the top layer of the skin.

Lesions or blisters form where skin naturally meets or rubs together, as in HS. They can also be found in or on the:

mouth, throat, eyes, nose, and genital areas

Pemphigus vulgaris is the most common kind of pemphigus. It affects 0.1 to 2.7 persons in every 100,000.

Pemphigus vegetans, a pemphigus vulgaris variation, accounts for 1 to 2% of pemphigus cases globally.

If untreated, Pemphigus vegetans can be lethal. The treatment focuses on removing the lesions or blisters and preventing them from recurring.

Corticosteroids and other anti-inflammatory steroids are frequently used as the first line of defense. In addition, you can have surgery to remove the lesions or blisters, while also cleaning and dressing the affected area on a daily basis.

Medicated mouthwash or clobetasol, a corticosteroid and ointment used to treat oral problems, are examples of mouth and throat remedies.

Crohn’s disease 

Crohn’s disease is an inflammatory bowel disease (IBD) of the digestive tract.

It affects around 780,000 Indians. Every year, approximately 38,000 new cases are reported. Researchers believe that genetics, the immune system, and the environment all have a role in Crohn’s disease development.

Between 20 and 33 percent of persons with Crohn’s disease have skin lesions as a result of the condition. This is referred to as a cutaneous epidemic.

Cutaneous lesions, which resemble genital warts, appear after bowel disease has shown on the skin or another organ outside of the intestinal tract. The eyes, liver, and gallbladder are all included. It might also have an impact on the joints.

If your Crohn’s disease and lesions have metastasized, or spread, they can become painful and potentially lethal. There are currently few therapy options for this stage.

Sneddon-Wilkinson syndrome

Sneddon-Wilkinson illness is characterized by clusters of pus sores on the skin. Subcorneal pustular dermatosis (SPD) is another name for it.

Experts are unsure what is causing it. The disease, which is uncommon and sometimes misunderstood, primarily affects persons over the age of 40, particularly women. As a result, its precise prevalence is uncertain.

Soft, pus-filled pimples occur between skin that rubs together a lot, just like in HS. Skin lesions appear on the body, between skin folds, and in the vaginal area. They “explode” as a result of friction.

This popping of the lesions may be accompanied by an itchy or burning feeling. These feelings are followed by scaling and discolouration of the skin. Despite being chronic and painful, this skin ailment is not lethal.

The antibiotic dapsone is the preferred treatment for this condition, with a daily dose of 50 to 200 milligrams (mg) taken orally.

Lichen planus 

Inverse lichen planus pigmentosus is an inflammatory disorder that causes skin fold discolouration and uncomfortable pimples.

Only about 20 cases have been documented worldwide, mostly affecting Asians. Nobody knows what is causing it.

Small clusters of flat lesions, or macules, of discolored skin appear. They don’t normally contain pus, but they do occasionally. Some people’s skin spontaneously clears up with time, whilst others may experience symptoms for years.

This is a mild condition that can be addressed with a topical treatment. Corticosteroids are the most often used treatments for wound healing and can even aid with pigmentation in some situations.

Dowling-Degos syndrome

Dowling-Degos disease is a hereditary illness that causes darker skin, especially in folds such as the armpit, groin, and joint areas.

Pigment changes can also affect the neck, hands, cheeks, and scalp, albeit they are less prevalent.

The majority of the lesions are minor and resemble blackheads, however red areas resembling acne might form around the lips.

Lesions on the scalp might also look as fluid-filled lumps. Itching and burning sensations are possible.

Skin changes, like HS, occur in late childhood or early adolescence.

However, some people do not have breakouts until they reach maturity. Dowling-Degos is not a life-threatening disease, but it can cause distress and worry in those who have it.

This disease presently has no cure. Treatments ranging from laser therapy to topical steroids to retinoids have been tried, but results have been mixed, and nothing has proven to be consistently successful.


If you have a skin issue, pay attention to your body and treat any signs seriously.

Consult your doctor who can assist you in obtaining a diagnosis and determining the best treatment options for your specific problems.


Know More About Ayurveda Treatments for Dermatology.