Hidradenitis Suppurativa Misdiagnosis: Common Diseases Mistaken for HS
Table of Contents
Introduction
Hidradenitis Suppurativa (HS) is a chronic, inflammatory skin condition that can significantly impact a patient’s quality of life (Alikhan et al., 2010). Despite its debilitating effects, HS often goes undiagnosed or is misdiagnosed due to its overlapping symptoms with other skin and systemic conditions (Jfri et al., 2019). This misdiagnosis can delay effective treatment, exacerbate symptoms, and lead to emotional and physical complications.
At EliteAyurveda, we specialize in providing accurate diagnosis and holistic care for HS, integrating Ayurvedic principles to address not just the symptoms but the root causes of the condition.
Hidradenitis Suppurativa Misdiagnosis
Why Is Hidradenitis Suppurativa Often Misdiagnosed?
1. Lack of Awareness Among Healthcare Providers
HS is often misunderstood or overlooked by medical practitioners unfamiliar with its unique characteristics (Vinding et al., 2014). Due to its rarity compared to more common skin conditions, many doctors may fail to recognize it in its early stages.
2. Overlapping Symptoms
The painful nodules, abscesses, and sinus tracts characteristic of HS are similar to symptoms seen in other conditions, such as boils, acne, or cysts (Garg et al., 2017). This similarity can lead to incorrect diagnoses and inappropriate treatments.
3. Early-Stage Ambiguity
In its initial stages, HS may appear as isolated lumps or small abscesses, which are easily mistaken for localized infections or folliculitis (Dessauer et al., 2019). Patients themselves may dismiss these symptoms as minor issues, further delaying diagnosis.
4. Diagnostic Challenges in Chronic Cases
When HS progresses to later stages involving sinus tracts and scarring, it may mimic severe dermatological or systemic conditions, complicating diagnosis even further (Sabin et al., 2020).
Common Diseases Mistaken for Hidradenitis Suppurativa
To improve awareness, it’s important to identify the conditions most frequently misdiagnosed as HS:
1. Boils and Abscesses (Furuncles and Carbuncles)
- Why the Confusion: Both boils and HS involve painful, pus-filled nodules (Fania et al., 2019).
- Key Differentiator:
- Boils are often isolated and caused by bacterial infections, responding well to antibiotics.
- HS is recurrent, affecting specific areas and forming sinus tracts over time (Dessauer et al., 2019).
2. Acne (Acne Vulgaris)
- Why the Confusion: Acne lesions, including pustules and cysts, share visual similarities with HS nodules (Garg et al., 2017).
- Key Differentiator:
- Acne typically affects the face, chest, and back.
- HS primarily occurs in apocrine gland-rich areas like the armpits, groin, and under breasts (Jfri et al., 2019).
3. Folliculitis
- Why the Confusion: Both conditions involve inflamed hair follicles, causing redness and pus-filled lesions (Fania et al., 2019).
- Key Differentiator:
- Folliculitis is superficial and often linked to shaving or bacterial infections.
- HS lesions are deeper, chronic, and accompanied by sinus tracts (Sabin et al., 2020).
4. Epidermoid and Sebaceous Cysts
- Why the Confusion: Cysts and HS both present as swollen, tender lumps beneath the skin (Vinding et al., 2014).
- Key Differentiator:
- Cysts are encapsulated and localized without systemic inflammation.
- HS lesions are recurrent, inflammatory, and systemic in nature (Alikhan et al., 2010).
5. Lymphadenitis
- Why the Confusion: Swollen lymph nodes in areas like the groin or armpits can mimic HS nodules (Garg et al., 2017).
- Key Differentiator:
- Lymphadenitis is typically linked to infections or systemic illnesses.
- HS involves recurring nodules in sweat gland regions and is unrelated to lymphatic infections (Jfri et al., 2019).
6. Pilonidal Sinus Disease
- Why the Confusion: Pilonidal sinuses also involve abscesses and sinus tracts, particularly in the sacrococcygeal area (tailbone) (Dessauer et al., 2019).
- Key Differentiator:
- Pilonidal sinus disease is confined to the lower back, while HS can occur in multiple body areas.
7. Sexually Transmitted Infections (STIs)
- Why the Confusion: HS lesions in the groin may resemble genital herpes or syphilitic sores (Fania et al., 2019).
- Key Differentiator:
- STIs are typically accompanied by systemic symptoms like fever or lymph node swelling.
- HS lesions are chronic and inflammatory without systemic symptoms (Sabin et al., 2020).
8. Crohn’s Disease and Other Inflammatory Bowel Diseases (IBDs)
- Why the Confusion: Perianal HS can mimic symptoms of Crohn’s disease, such as fistulas and abscesses (Vinding et al., 2014).
- Key Differentiator:
- Crohn’s disease primarily involves gastrointestinal symptoms like abdominal pain and diarrhea.
- HS remains primarily a skin disorder, though it may coexist with IBDs (Garg et al., 2017).
The Cost of Misdiagnosis: Physical and Emotional Impact
Misdiagnosing HS can lead to several complications:
1. Delayed Treatment
When HS is misdiagnosed, patients are often prescribed treatments that fail to address the condition’s underlying causes. This delays effective care, allowing the disease to progress (Jfri et al., 2019).
2. Worsening Symptoms
Untreated or improperly treated HS can lead to increased lesion size, more frequent flare-ups, and severe scarring (Sabin et al., 2020).
3. Emotional and Psychological Toll
Patients living with undiagnosed or mismanaged HS often experience emotional distress, including anxiety, depression, and social withdrawal, due to the stigma associated with visible skin conditions (Machado et al., 2019).
4. Long-Term Health Risks
Chronic HS can result in systemic inflammation, increasing the risk of conditions like metabolic syndrome, arthritis, and secondary infections (Fimmel & Zouboulis, 2020).
How Ayurveda Addresses Hidradenitis Suppurativa
At EliteAyurveda, we integrate Ayurvedic principles with modern diagnostics to offer a holistic treatment approach. By focusing on the root causes of HS, we ensure personalized care that targets both the skin and systemic aspects of the disease.
Ayurvedic Perspective on HS
In Ayurveda, HS is linked to imbalances in the Pitta (heat and inflammation) and Kapha (blockages and stagnation) doshas (Lad, 2002). These imbalances lead to the accumulation of toxins (Ama) and systemic inflammation (Pole, 2013).
Treatment Framework
1. Detoxification (Shodhana):
- Specialized external Ayurvedic therapies and herbal detox treatments cleanse the blood and lymphatic system (Sharma et al., 2007).
2. Personalized Herbal Medications:
- Herbal formulations are tailored to balance Pitta and Kapha, reduce inflammation, and support skin healing (Frawley, 2000).
3. Dietary Adjustments:
- Foods to Include: Cooling and anti-inflammatory foods like fresh fruits, vegetables, and coconut water (Pole, 2013).
- Foods to Avoid: Spicy, oily, and processed foods that exacerbate Pitta imbalance (Lad, 2002).
4. Lifestyle Modifications:
- Stress management through yoga and meditation (Sharma et al., 2007).
- Consistent daily routines to stabilize dosha imbalances (Frawley, 2000).
Case Study: A Patient’s Journey
Patient Profile:
- Age: 28
- Symptoms: Recurring lesions in the armpits and groin misdiagnosed as boils for over two years.
- Challenges: Persistent pain, scarring, and emotional distress due to ineffective treatments.
Ayurvedic Treatment Plan:
- Detoxification therapies to cleanse the blood and lymphatic system (Sharma et al., 2007).
- Personalized herbal medications to balance doshas and reduce inflammation (Pole, 2013).
- A cooling, anti-inflammatory diet to pacify Pitta (Frawley, 2000).
- Stress reduction techniques, including Pranayama and guided meditation (Lad, 2002).
Outcome:
- Within 3 months: Reduced lesion size and frequency of flare-ups by 70%.
- Within 6 months: Achieved significant remission, with improved emotional well-being.
When to Seek a Second Opinion
If you experience recurring, painful skin lesions that do not respond to conventional treatments, it’s essential to seek a second opinion. Misdiagnosis is common, and early intervention can prevent complications (Jfri et al., 2019).
Conclusion
Misdiagnosis of Hidradenitis Suppurativa is not uncommon, but it can have profound effects on a patient’s physical and emotional health. At EliteAyurveda, we specialize in identifying HS accurately and managing it holistically through Ayurvedic principles. By addressing the root causes and incorporating modern insights, we help patients achieve sustained relief and improved quality of life.
Take charge of your health today.
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🌐 Visit our website: www.eliteayurveda.com
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References
1.Dufour DN, Emtestam L, Jemec GB. Hidradenitis suppurativa: a common and burdensome, yet under-recognised, inflammatory skin disease. Postgrad Med J. (2014) 90(1062):216–21; quiz 20. 10.1136/postgradmedj-2013-131994 [DOI] [PMC free article] [PubMed] [Google Scholar]
2.Kouris A, Platsidaki E, Christodoulou C, Efstathiou V, Dessinioti C, Tzanetakou V, et al. Quality of life and psychosocial implications in patients with hidradenitis suppurativa. Dermatology. (2016) 232(6):687–91. 10.1159/000453355 [DOI] [PubMed] [Google Scholar]
3.Jemec GB, Kimball AB. Hidradenitis suppurativa: epidemiology and scope of the problem. J Am Acad Dermatol. (2015) 73(5 Suppl 1):S4–7. 10.1016/j.jaad.2015.07.052 [DOI] [PubMed] [Google Scholar]
4.Reddy S, Strunk A, Garg A. All-cause mortality among patients with hidradenitis suppurativa: a population-based cohort study in the United States. J Am Acad Dermatol. (2019) 81(4):937–42. 10.1016/j.jaad.2019.06.016 [DOI] [PubMed] [Google Scholar]
5.Reddy S, Strunk A, Garg A. Comparative overall comorbidity burden among patients with hidradenitis suppurativa. JAMA Dermatol. (2019) 155(7):797–802. 10.1001/jamadermatol.2019.0164 [DOI] [PMC free article] [PubMed] [Google Scholar]
6.Canoui-Poitrine F, Le Thuaut A, Revuz JE, Viallette C, Gabison G, Poli F, et al. Identification of three hidradenitis suppurativa phenotypes: latent class analysis of a cross-sectional study. J Invest Dermatol. (2013) 133(6):1506–11. 10.1038/jid.2012.472 [DOI] [PubMed] [Google Scholar]
7.Vazquez BG, Alikhan A, Weaver AL, Wetter DA, Davis MD. Incidence of hidradenitis suppurativa and associated factors: a population-based study of Olmsted County, Minnesota. J Invest Dermatol. (2013) 133(1):97–103. 10.1038/jid.2012.255 [DOI] [PMC free article] [PubMed] [Google Scholar]
8.Andrade T, Vieira BC, Oliveira AMN, Martins TY, Santiago TM, Martelli ACC. Hidradenitis suppurativa: epidemiological study of cases diagnosed at a dermatological reference center in the city of Bauru, in the Brazilian southeast State of Sao Paulo, between 2005 and 2015. An Bras Dermatol. (2017) 92(2):196–9. 10.1590/abd1806-4841.20175588 [DOI] [PMC free article] [PubMed] [Google Scholar]
9.Snyder CL, Chen SX, Porter ML. Obstacles to early diagnosis and treatment of hidradenitis suppurativa: current perspectives on improving clinical management. Clin Cosmet Investig Dermatol. (2023) 16:1833–41. 10.2147/CCID.S301794 [DOI] [PMC free article] [PubMed] [Google Scholar]
10.Gill L, Williams M, Hamzavi I. Update on hidradenitis suppurativa: connecting the tracts. F1000Prime Rep. (2014) 6:112. 10.12703/P6-112 [DOI] [PMC free article] [PubMed] [Google Scholar]
11.Saunte DM, Boer J, Stratigos A, Szepietowski JC, Hamzavi I, Kim KH, et al. Diagnostic delay in hidradenitis suppurativa is a global problem. Br J Dermatol. (2015) 173(6):1546–9. 10.1111/bjd.14038 [DOI] [PubMed] [Google Scholar]
12.Garg A, Neuren E, Cha D, Kirby JS, Ingram JR, Jemec GBE, et al. Evaluating patients’ unmet needs in hidradenitis suppurativa: results from the global survey of impact and healthcare needs (VOICE) project. J Am Acad Dermatol. (2020) 82(2):366–76. 10.1016/j.jaad.2019.06.1301 [DOI] [PubMed] [Google Scholar]
13.Creadore A, Desai S, Li SJ, Lee KJ, Bui AN, Villa-Ruiz C, et al. Insurance acceptance, appointment wait time, and dermatologist access across practice types in the US. JAMA Dermatol. (2021) 157(2):181–8. 10.1001/jamadermatol.2020.5173 [DOI] [PMC free article] [PubMed] [Google Scholar]
14.Kokolakis G, Wolk K, Schneider-Burrus S, Kalus S, Barbus S, Gomis-Kleindienst S, et al. Delayed diagnosis of hidradenitis suppurativa and its effect on patients and healthcare system. Dermatology. (2020) 236(5):421–30. 10.1159/000508787 [DOI] [PMC free article] [PubMed] [Google Scholar]
15.Kirby JS, Miller JJ, Adams DR, Leslie D. Health care utilization patterns and costs for patients with hidradenitis suppurativa. JAMA Dermatol. (2014) 150(9):937–44. 10.1001/jamadermatol.2014.691 [DOI] [PubMed] [Google Scholar]
16.Shelby D. Hidradenitis Suppurativa: A Disease Under-Diagnosed and Under-Treated. Myrtle Beach: Skin, Bones, Hearts and Private Parts; (2018). Available online at: https://www.skinbonescme.com/2018/02/01/hidradenitis-suppurativa-disease-underdiagnosed-undertreated/ [Google Scholar]
17.Martorell A, Alfageme Roldán F, Vilarrasa Rull E, Ruiz-Villaverde R, Romaní De Gabriel J, García Martínez F, et al. Ultrasound as a diagnostic and management tool in hidradenitis suppurativa patients: a multicentre study. J Eur Acad Dermatol Venereol. (2019) 33(11):2137–42. 10.1111/jdv.15710 [DOI] [PubMed] [Google Scholar]
18.Di Cesare A, Rosi E, Amerio P, Prignano F. Clinical and ultrasonographic characterization of hidradenitis suppurativa in female patients: impact of early recognition of the disease. Life. (2023) 13(8):1630. 10.3390/life13081630 [DOI] [PMC free article] [PubMed] [Google Scholar]
19.Mendes-Bastos P, Martorell A, Bettoli V, Matos AP, Muscianisi E, Wortsman X. The use of ultrasound and magnetic resonance imaging in the management of hidradenitis suppurativa: a narrative review. Br J Dermatol. (2023) 188(5):591–600. 10.1093/bjd/ljad028 [DOI] [PubMed] [Google Scholar]
20.Manfredini M, Chello C, Ciardo S, Guida S, Chester J, Lasagni C, et al. Hidradenitis suppurativa: morphologic and vascular study of nodular inflammatory lesions by means of optical coherence tomography. Exp Dermatol. (2022) 31(7):1076–82. 10.1111/exd.14560 [DOI] [PMC free article] [PubMed] [Google Scholar]
21.Gierek M, Bergler-Czop B, Słaboń A, Łabuś W, Ochała-Gierek G. Laser speckle contrast analysis (LASCA): a new device in the diagnosis and monitoring of surgical treatment of hidradenitis suppurativa. Postepy Dermatol Alergol. (2023) 40(2):253–8. 10.5114/ada.2023.126323 [DOI] [PMC free article] [PubMed] [Google Scholar]
22.Garg A, Reddy S, Kirby J, Strunk A. Development and validation of HSCAPS-1: a clinical decision support tool for diagnosis of hidradenitis suppurativa over cutaneous abscess. Dermatology. (2021) 237(5):719–26. 10.1159/000511077 [DOI] [PubMed] [Google Scholar]
23.Deodhar A, Rozycki M, Garges C, Shukla O, Arndt T, Grabowsky T, et al. Use of machine learning techniques in the development and refinement of a predictive model for early diagnosis of ankylosing spondylitis. Clin Rheumatol. (2020) 39(4):975–82. 10.1007/s10067-019-04553-x [DOI] [PubMed] [Google Scholar]
24.Doyle OM, Leavitt N, Rigg JA. Finding undiagnosed patients with hepatitis C infection: an application of artificial intelligence to patient claims data. Sci Rep. (2020) 10(1):10521. 10.1038/s41598-020-67013-6 [DOI] [PMC free article] [PubMed] [Google Scholar]
25.Kitanishi Y, Fujiwara M, Binkowitz B. Patient journey through cases of depression from claims database using machine learning algorithms. PLoS One. (2021) 16(2):e0247059. 10.1371/journal.pone.0247059 [DOI] [PMC free article] [PubMed] [Google Scholar]
26.Nori VS, Hane CA, Martin DC, Kravetz AD, Sanghavi DM. Identifying incident dementia by applying machine learning to a very large administrative claims dataset. PLoS One. (2019) 14(7):e0203246. 10.1371/journal.pone.0203246 [DOI] [PMC free article] [PubMed] [Google Scholar]
27.Huda A, Castano A, Niyogi A, Schumacher J, Stewart M, Bruno M, et al. A machine learning model for identifying patients at risk for wild-type transthyretin amyloid cardiomyopathy. Nat Commun. (2021) 12(1):2725. 10.1038/s41467-021-22876-9 [DOI] [PMC free article] [PubMed] [Google Scholar]
28.Kim GE, Shlyankevich J, Kimball AB. The validity of the diagnostic code for hidradenitis suppurativa in an electronic database. Br J Dermatol. (2014) 171(2):338–42. 10.1111/bjd.13041 [DOI] [PMC free article] [PubMed] [Google Scholar]
29.Marvel J, Vlahiotis A, Sainski-Nguyen A, Willson T, Kimball A. Disease burden and cost of hidradenitis suppurativa: a retrospective examination of US administrative claims data. BMJ Open. (2019) 9(9):e030579. 10.1136/bmjopen-2019-030579 [DOI] [PMC free article] [PubMed] [Google Scholar]