Crohn's Disease Causes
Part of the Inflammatory Bowel Disease Centre
The five internal driver systems. In Crohn’s the gut barrier and immune regulation are the PRIMARY drivers, not secondary ones.
Gut Barrier Failure in Crohn's Disease
Crohn's begins with a failing gut barrier. Intestinal permeability is measurable before disease appears, which is why barrier repair drives real correction.
Read more →Gut Microbiome and Crohn's Disease
Reduced diversity, lost butyrate producers and adherent-invasive strains: how the Crohn's microbiome sustains inflammation, and why antibiotics backfire.
Read more →Immune Dysregulation in Crohn's Disease
In Crohn's the immune system cannot clear what crosses the gut barrier, so it escalates. Why suppressing one arm of it does not break the escalation loop.
Read more →Diet Triggers in Crohn's Disease
There is no universal Crohn's diet. What emulsifiers and ultra-processed food do to the mucus layer, and why fibre depends on whether you have a stricture.
Read more →Stress and Cortisol in Crohn's Disease
Stress is not in your head. Cortisol dysregulation alters gut permeability, motility and immune signalling directly, and the effect arrives on a long lag.
Read more →Speak to a specialist about your Crohn's
A consultation assesses your driver profile and what root-cause correction can realistically achieve in your case. If we do not think we can help you, we will tell you.
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